Some of the growth and healing factors found in BMAC include:
Stem cell therapy may be useful in the following clinical conditions:
Tendonitis (Chronic tendonitis or partial-thickness tears)
Degenerative Joint Disease
At the The Kentucky PRP and Stem Cell Institute, we only use stem cells derived from the patient's own body in order to minimize the risk of allergic reaction or disease transmission. Embryonic stem cells and stem cells that are manipulated outside the body remain very controversial and in some instances illegal to use in the United States. We are able to get your own stem cells from bone marrow aspiration which is a procedure that can be done in the office with minimal discomfort. The two primary sources of bone marrow we use are the posterior iliac crest (posterior hip) and the proximal tibia below the knee. The bone marrow regenerates and multiple procedures can be done over time. After drawing out the bone marrow, the stem cells are then concentrated using FDA approved commercially available machine to create bone marrrow aspirate concentrate (BMAC) which can then be injected into an area requiring stem cell therapy. The BMAC concentrating process takes approximately 15 minutes in the office.
We do not obtain stem cells from adipose tissue (fat) for several clinical reasons. It has been shown in at least 13 published papers that bone marrow derived stem cells are significantly better than fat derived stem cells for cartilage repair (osteoartitis treatments as an example).
Furthermore, the United States FDA has issued public guidance that is considers manipulation (enzymatic degradation) of fat to get stem cells to be equivalent to creating a drug, and therefore will fall under FDA drug manufacture guidelines. It is very unlikely that an office based system that obtains stem cells from fat without enzymatic degradation would produce sufficient yield of stem cells to be clinically useful, and even then they would not be as active for orthopedic applications as bone marrow derived cells.
Ultimately, the reasons we do not use stem cells derived from fat are as follows:
Experimental data has shown that doctors can increase the amount of stem cells obtained in a bone marrow harvest by drawing smaller volumes from multiple sites. Typically we use 2-6 harvest sites and 10cc or less volume draws in order to maximize the number of stem cells we obtain.
Just one or two bandaids to cover up the harvest site(s) and the patient walks out of the office!
Depending on the specific area being treated, crutches or upper body immobilization may not necessary. If immobilization is necessary then typically it can be stopped after 2 days. Most patients will have some soreness for up to 48 hours that should decrease. Patient may use tylenol or other non anti-inflammatory pain medications. NSAIDs and other anti-inflammatories should be avoided in the post-procedure period because they block the response that leads to healing. Patients should refrain from significant physical activity or sports activities for about a week after the procedure. Patients are re-evaluated between 4-6 weeks after the procedure to evaluate their progress and to make further treatment recommendations.
In the United States, insurance plans and Medicare/Medicaid do not currently cover BMAC/Stem Cell therapy. Patients interested in having BMAC therapy are responsible for the full payment for the procedure.
Our doctors do not want cost to be a factor for patients who wish to have Stem Cell therapy and we have clinical specialists who can help with billing and payment concerns.
Please call our specialists first at 502-370-8001 for any questions on cost or payment plans.